CHEMICAL PROCESSING STEPS
OF SPLENDA MANUFACTURING
Sucrose is tritylated with tritylchloride; This is performed in the presence of dimethylformamide and 4 - methylmorpholine.
The tritylated sucrose is then acetylated with acetic anhydride....
The resulting TRISPA (6,1',6' - tri - O -trityl - penta - O - acetylsucrose) is then chlorinated with hydrogen chloride, in the presence of toluene.
The resulting 4 - PAS (sucrose - 2,3,4,3',4' - penta-acetate) is then heated in the presence of methyl isobutyl ketone and acetic acid.
The resulting mixture, 6 - PAS (sucrose - 2,3,6,3',4' - penta-acetate) is again chlorinated with thionyl chloride, in the presence of toluene and benzyltriethylammoniumchloride...............and,
The resulting TOSPA (sucrose pena-acetate) is then treated with methanol, in the presence of sodium methoxide which produces the commercial product we call:
