Posted: 13 August 2007
From: Dr. Betty Martini, D.Hum., Bettym19@mindspring.com
To: Commissioner-fda.gov, mitchell.cheeseman-fda.hhs.gov, laura.tarantino-fda.hhs.gov, LJAFFE@OC.FDA.GOV, firstname.lastname@example.org, david.acheson-fda.hhs.gov, inforeply-cdc.gov
Date: Mon, Aug 13, 2007 10:52 am
Subject: Aspartame Imminent Health Hazard, Must Be Banned Immediately. Violates Delaney. 2004 statistics, #2 cause of death malignant neoplasms. CERTIFIED MAIL
Be sure to see "The CDC - Deaths: Preliminary Data For 2004" which may be found at" http://www.cdc.gov/nchs/products/pubs/pubd/hestats/prelimdeaths04/preliminarydeaths04.htm
Dr. Von Eschenbach:
Over and over again appeals courts have ruled there is no exemption for trivial amounts of cancer by the Delaney Amendment. Your own FDA toxicologist, Dr. Adrian Gross, who investigated aspartame on site and requested an investigation by the Justice Department exposed FDA for not invoking Delaney to Congress:
August 1, l985: Dr. Adrian Gross, told Congress at least one of Searle's studies "has established beyond ANY REASONABLE DOUBT that aspartame is capable of inducing brain tumors in experimental animals and that this predisposition of it is of extremely high significance.
... In view of these indications that the cancer causing potential of aspartame is a matter that had been established WAY BEYOND ANY REASONABLE DOUBT, one can ask: What is the reason for the apparent refusal by the FDA to invoke for this food additive the so-called Delaney Amendment to the Food, Drug and Cosmetic Act?"
The Delaney Amendment makes it illegal to allow any residues of cancer causing chemicals in foods. In his concluding testimony Gross asked, "Given the cancer causing potential of aspartame how would the FDA justify its position that it views a certain amount of aspartame as constituting an allowable daily intake or 'safe' level of it? Is that position in effect not equivalent to setting a 'tolerance' for this food additive and thus a violation of that law? And if the FDA itself elects to violate the law, who is left to protect the health of the public?" Congressional Record SID835:131 (August 1, l985)
When I sent out the first notice showing Court of Appeals has always upheld Delaney people complained FDA immediately removed the article from the web site. That simply shows intent to cover up the fact the Delaney Amendment makes aspartame illegal and is a food law that places an absolute prohibition on carcinogenic substances in food.
Michael Taylor who wrote the de minimis knew it was illegal for him to do so because the Appeals Court had said it was forbidden. See more articles below.
Senator Orrin Hatch of Utah tried to prevent congressional hearings on aspartame and indeed one of his press releases said "Hatch Says No To Congressional Hearings on Aspartame". He received money from Monsanto and some believe, he is the reason the bill to put a moratorium on aspartame and have NIH do independent studies never got out of committee. These studies would have been on the problems currently seen in the population which today are epidemic; seizures, behavioral problems, interaction with drugs and fetal damage. If a product is safe manufacturers don't try to block studies being done. Even Dr. Richard Wurtman was threatened by the VP of Searle if he did studies on aspartame and seizures he would have his research funds rejected which he did.
The New York Times interviewed Senator Hatch just before aspartame was approved and on June 26, l981 stated:
"Two Republican Senators, Orrin G. Hatch of Utah, chairman of the Labor and Resources Committee, and Jesse Helms of North Carolina, chairman of the Agriculture committee, introduced a bill redefining a safe chemical as one that shows an "absence of significant risk." The legislation, which includes many provisions that the food industry had sought, would gradually eliminate instead of banning substances found to be carcinogenic and would allow exceptions to the Delaney Amendment, a food law that places an absolute prohibition on carcinogenic substances in food."
More articles below show that years later appeal courts still upheld the Delaney Amendment with no exemption at any dose. Senator Hatch when interviewed in June, 1981 also said: "However, the existing statutes are antiquated, and these agencies are forced to make regulatory decisions that are sometimes widely perceived as irrational and not in the public interest."
So what Senator Hatch perceives as antiquated and irrational is adhering to the Delaney Amendment safe guarding the food from cancer causing products. Hatch said further, "But some degree of risk is inherent". Maybe if Senator Hatch had to walk in the moccasins of aspartame cancer victims he might feel differently. Kelli Motluck with a head full of aspartame brain tumors cried out, "I want to live, I want to live, I want to live, but if I die, promise me you will tell the world Monsanto murdered me!" She left a grieving husband and a small child who would grow up without her mother. The cases never end.
FDA revoked the petition for approval when Don Rumsfeld was CEO of Searle. Rumsfeld said he would call in his markers as discussed in the l985 congressional record, and 8 month investigation of aspartame by Gregory Gordon. He was on President Reagan's transition team, and the day after he took office he appointed Hayes as FDA Commissioner. The current FDA Commissioner was asked to resign, and Reagan wrote an executive order making the FDA then powerless to do anything about aspartame until Hayes got there. He then over-ruled the Board of Inquiry that revoked the petition, knowing full well aspartame violated the Delaney Amendment.
The late Dr. Adrian Gross, FDA toxicologist, on August 1 l985 (Senate page 10840) questioned how FDA could even set an allowable dose of a product that caused cancer and violated the Delaney Amendment. His last words to Congress were: "And if the FDA itself elects to violate the law, who is left to protect the health of the people?" When will FDA answer that question?
Michael Decourcy Hinds of the New York Times interviewed Arthur Hull Hayes in July, l982. He said: "You support proposals to ease the food safety laws, particularly those restricting the use of food additives. How would this benefit consumers?" Hayes answered, "The laws are not always flexible enough. They currently mandate, for example, that if a food additives causes cancer at any dose in any species of animal, it may not be licensed. It doesn't matter that the incidence of cancer was minuscule or that it occurred only in mice and only at extremely large dosage levels. It doesn't matter that science has changed since l938, when many of the food laws were passed, or the l950's when they were amended."
What Arthur Hull Hayes was doing was excusing himself because he violated the Delaney Amendment when he approved aspartame after the Board of inquiry had revoked the petition. As Dr. Ralph Walton pointed out in his research on aspartame scientific peer reviewed studies and funding, 92% of independent or unbiased scientific peer reviewed studies not only show the problems but if you eliminate 6 the FDA had something to do with and one pro-aspartame summary, 100% show the problems aspartame triggers. Yet no study that is controlled or funded by aspartame makers ever shows a problem. http://www.dorway.com/peerrev.html
One thing that hasn't changed is manufacturers continuing to rig studies to defend their products in the name of science. As an example, flawed research on aspartame and seizures: http://www.holisticmed.com/aspartame/abuse/seizures.html
When you read the interviews of Hatch and Hayes you realize they must be very good friends with loyalty to aspartame manufacturers and no concern for the population ingesting this carcinogenic deadly chemical.
The Center for Disease Control recently published the preliminary data for 2004 regarding deaths. Number 2 is malignant neoplasms (cancer). What would you expect with 70% of the population and 40% of children consuming a multipotential carcinogen? Because aspartame was approved by political chicanery instead of science FDA should have recalled it years ago.
From FDA's own audit, The Bressler Report:
The finding of ovarian neoplasms in animals H19CF, H19C, and H7HF, and the finding of diffuse hyperplasia in animal D29CF, which were not diagnosed by Searle.
A mammary tumor found in animal F27CF was described as a papillary cystadenoma on the pathology summary sheet, (page 105, Vol. II of the submission) and as an adenocarcinoma on summary table 12 (p. 95, Vol. I of the submission).
Female Rat No. H10CF (Path 95624) Ovary - Neoplasm - probably granulosa cell tumor.
Female Rat No. H19CF (Path. No. 95626) Kidney - Focal calcification.
Ovary - Neoplasm - probably granulosa cell tumor.
Female Rat No. H7HF (Path No. 95623) Ovary - Neoplasm - probably granulosa cell tumor.
Female Rat No. H15HF (Path No. 95665) Lymph Node - The diagnosis of lymphoma, benign, was present on the Searle microscopic report. According to Dr. Frith, lymphoma is generally not considered to be benign and he would diagnose lymphosarcoma.
Female Rat No. D10Lf (Path No. 92521) Subcutaneous mass was diagnosed as an angiofibroma on Searle report. The lesion is more consistent with an angiosarcoma.
This doesn't even go into the brain tumors that were excised from the rats FDAs own audit, http://www.dorway.com/bressler.txt Furthermore, Jerome Bressler told Doctors H. J. Roberts and Russell Blaylock, and myself, when this audit was retyped FDA removed the worst 20%. No wonder FDA told Dr. Roberts congressman they refuse to release the other 20%. More carcinoma???
When Dr. M Soffritti reported the Ramazzini Study in 2005 showing aspartame was a multipotential carcinogen showing lymphoma, leukemia, etc. FDA already knew aspartame causes cancer. The second study by Ramazzini shows how little it takes of aspartame to cause cancer. Here are summaries of both studies:
The first ERF study (2005) was conducted on 1800 Sprague-Dawley rats (100-150/per sex/per group). In order to simulate daily human intake, aspartame was added to the standard rat diet in quantities of 5000, 2500, 100, 500, 20, 4, and 0 mg/Kg of body weight. Treatment of the animals began at 8 weeks of age and continued until spontaneous death. The results show that APM causes a statistically significant, dose-related increase of lymphomas/leukemias and malignant tumors of the renal pelvis in females and malignant tumors of peripheral nerves in males. These results demonstrate for the first time that APM is a carcinogenic agent, capable of inducing malignancies at various dose levels, including those lower than the current acceptable daily intake (ADI) for humans (50 mg/kg of body weight in the US, 40 mg/kg of body weight in the EU).
The second ERF study (2007) was conducted on 400 Sprague-Dawley rats (70-95/per sex/per group). In order to simulate daily human intake, aspartame was added to the standard rat diet in quantities of 100, 20, and 0 mg/Kg of body weight. Treatment of the animals began on the 12th day of fetal life until natural death. The results of the second study show an increased incidence of lymphomas/leukemias in female rats with respect to the first study. Moreover, the study shows that when lifespan exposure to APM begins during fetal life, the age at which lymphomas/leukemias develop in females is anticipated. For the first time, a statistically significant increase in mammary cancers in females was also observed in the second study. The results of this transplacental carcinogenicity bioassay not only confirm, but also reinforce the first experimental demonstration of APMs multipotential carcinogenicity.
FDA tried to rebut the first Ramazzini Study which was peer reviewed by 7 world experts even though they had known for a quarter of a century aspartame causes cancer and had revoked the petition for approval because of the brain tumor issue, and the fact it couldn't be proven safe. Trying to use a ten year old multifood form (The Oatmeal Brownie Study) that only mentioned aspartame once in 56 questions was shameful. http://www.wnho.net/halt_the_spin_on_bogus_studies.htm
So why has FDA not recalled aspartame because of the second study? 12 Eminent US Toxicologists call for Aspartame ban SCIENCE VOL 317 6 JULY 2007 page 31
Furthermore aspartame experts like Doctors Roberts, Blaylock, and Walton have said it needs to be banned for years. My Citizens Petition for ban written 6 years ago has not been answered even though the law says FDA has only 180 days. James Turner, Atty, has also petitioned for a ban.
Study on oncogene activation and aspartame. http://www.wnho.net/gombos_in_vivo_2007.pdf
Aspartame is an imminent health hazard. Under the Delaney Amendment which FDA violated in the approval of aspartame it must be recalled.
Besides cancer aspartame has triggered all types of neurodegenerative diseases. It can precipitate diabetes, and a study at the University of Texas has shown the link between diet drinks and obesity. Aspartame makes you crave carbohydrates. It also interacts with all drugs and vaccines. Medical texts such as Aspartame Disease: An Ignored Epidemic by H. J. Roberts, M.D. and Excitotoxins: The Taste That Kills by Russell Blaylock, M.D., have gone into great detail on the mechanisms by which aspartame can precipitate disease and trigger symptoms on FDAs own list of 92 reactions including death. After a quarter of a century on the market and three congressional hearings because of the outrage of the public being poisoned it has clearly been proven aspartame disease is now a global epidemic.
An epidemic of diabetes rages as professional organizations, the manufacturer and FDA push aspartame (NutraSweet/Equal/Spoonful,E951, 951, Canderel, Benevia, etc.) on diabetics knowing full well that aspartame can precipitate diabetes, simulates and aggravates diabetic retinopathy and neuropathy, destroys the optic nerve, causes diabetics to go into convulsions and interacts with insulin. The free methyl alcohol is causing them to lose limbs. Diabetes is now the 6th leading cause of death. Diabetic specialist, H. J. Roberts, M.D., in his medical text, Aspartame Disease: An Ignored Epidemic, and other books and papers has been warning about this since this addictive excitoneurotoxic carcinogenic drug was approved.
On the report for Centers for Disease Control and Prevention's National Center for Health Statistics the number one cause of death is heart disease. Aspartame triggers an irregular heart rhythm, interacts with all cardiac medication, damages the cardiac conduction system and causes sudden death. Defibrillators are now sold across the counter. The Trocho Study in l998 shows the formaldehyde converted from the free methyl alcohol embalms living tissue. Clearly Death and embalming are not acceptable costs of business! The third leading cause of infant mortality is sudden infant death syndrome. With absolutely no concern for even the defenseless baby you have allowed aspartame in pediatric products. Their little heart cannot fight this deadly chemical. Combined with vaccines with deadly thimerosal what chance do they have? Here is what Dr. Russell Blaylock wrote about front groups pushing this poison on pregnant women. http://www.wnho.net/mh_aspartame_letter.htm
You have no excuse not to recall aspartame since FDA's own records have clearly proven aspartame is a multipotential carcinogen, which independent peer reviewed studies have confirmed. FDA is clearly implicated in 20% of the Bressler Report or FDA audit being withheld from the public. This can mean FDA knew about more cancers. Furthermore, FDA's excuse in the New York Times about the Ramazzini Study, that it would hurt the manufacturers profit, clearly shows FDA's loyalty to manufacturers who poison the public rather than the consumer public who have been betrayed.
As a study on additives sponsored by Food Standards in the UK shows behavioral problems in children, large chains like Sainsburys, Marks & Spencer, Tesco, etc. have already announced they are removing aspartame from their personal products. Not a word from FDA.
Food Standards in New Zealand says no studies were ever done in New Zealand. They relied on the FDA. People all over the world have relied on the FDA and clearly have been betrayed.
H. J. Roberts, M.D., just published a new book, "Protecting Mankind, One Physician's Quest", http://www.sunsentpress.com He quotes Exekiel 33:6 which says: "The watchman on the wall who sees danger, yet does not sound the trumpet or help his fellow man, will have the blood of the injured on his hands." Today the FDA is drenched in the blood of the victims betrayed.
As Senator Gaylord Nelson once said, "Food additives are big business. The chemical and drug industries have joined the food industry in a food-industrial complex that the FDA is supposed to regulate. The result is a proliferation of food chemicals that are unnecessary; an unknown number that are unsafe, many of them untested and most of them poorly monitored, at best." Aspartame disease has poisoned the world as reports flood in from around the globe. Now shown in film, "Sweet Misery: A Poisoned World."
Dr. Betty Martini
Founder, Mission Possible World Health International
9270 River Club Parkway
Duluth, Georgia 30097
Aspartame Toxiocity Center: http://www.holisticmed.com/aspartame