Compiled By Rich Murray, MA
Room For All
1943 Otowi Road
Santa Fe, New Mexico 87505 USA
Telephone: 505-501-2298
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Posted: 23 February 2010

Aspartame abstinance cures fibromyalgia chronic pain in 2 French adults: R Ciappuccini et al, Clin Exp Rheumatol 2010 Nov: Rich Murray 2010.02.19
Saturday, February 19, 2011
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Clin Exp Rheumatol. 2010 Nov-Dec;28(6 Suppl 63):S131-3. Epub 2010 Dec 22.
Aspartame-induced fibromyalgia, an unusual but curable cause of chronic pain.
Ciappuccini R,
Ansemant T,
Maillefert JF,,
Tavernier C,
Ornetti P,,
Department of Rheumatology, Dijon University Hospital, Burgundy University, Faculty of Medicine, Dijon, France.


We report for the first time an unusual musculoskeletal adverse effect of aspartame in two patients.

A 50-year-old woman had been suffering from widespread pain and fatigue for more than 10 years leading to the diagnosis of fibromyalgia.

During a vacation in a foreign country, she did not suffer from painful symptoms since she had forgotten to take her aspartame. All of the symptoms reappeared in the days following her return when she reintroduced aspartame into her daily diet. Thus, aspartame was definitively excluded from her diet, resulting in a complete regression of the fibromyalgia symptoms.

A 43-year-old man consulted for a 3-year history of bilateral forearm, wrist, and hand and cervical pain with various unsuccessful treatments. A detailed questioning allowed to find out that he had been taking aspartame for three years. The removal of aspartame was followed by a complete regression of pain, without recurrence. We believe that these patients' chronic pain was due to the ingestion of aspartame, a potent flavouring agent, widely used in food as a calorie-saver.

The benefit/ risk ratio of considering the diagnosis of aspartame-induced chronic pain is obvious: the potential benefit is to cure a disabling chronic disease, to spare numerous laboratory and imaging investigations, and to avoid potentially harmful therapies; the potential risk is to temporarily change the patient's diet.

Thus, practitioners should ask patients suffering from fibromyalgia about their intake of aspartame. In some cases, this simple question might lead to the resolution of a disabling chronic disease. PMID: 21176433


Woodrow C Monte, PhD, Emiritus Prof. Nutrition gives many PDFs of reseach -- methanol (11% of aspartame) puts formaldehyde into brain and body -- multiple sclerosis, Alzheimer's, cancers, birth defects, headaches: Rich Murray 2010.05.13
Thursday, May 13, 2010

[Other formaldehyde sources include alcohol drinks and tobacco and wood smoke, while adequate folic acid levels protect most people.]

589 references, many abstracts and full texts

Methanol: Where Is It Found? How Can It Be Avoided?

AVOID the following, ranked in order of greatest danger:

  1. Cigarettes.
  2. Diet foods and drinks with aspartame.
  3. Fruit and vegetable products and their juices in bottles, cans, or pouches.
  4. Jellies, jams, and marmalades not made fresh and kept refrigerated.
  5. Black currant and tomato juice products, fresh or processed.
  6. Tomato sauces, unless first simmered at least 3 hours with an open lid.
  7. Smoked food of any kind, particularly fish and meat.
  8. Sugar-free chewing gum.
  9. Slivovitz: You can consume one alcoholic drink a day on this diet -- no more! [No fruit brandies]
  10. Overly ripe or near rotting fruits or vegetables.

Selection from Article 2, Fitness Life, December 2007, and well discussed in the DVD video:

"Identical Symptoms of MS, Methanol Poisoning and Aspartame Toxicity"

The symptoms of multiple sclerosis (44, 83, 85, 169), chronic and acute methanol poisoning (13, 144, 189), and Aspartame toxicity (54, 58, 93, 181), are in all ways identical.

There is nothing that happens to the human body from the toxic effect of methanol that has not been expressed during the course of MS... nothing (143, 144).

This generalization extends even to the remarkable opthomological conditions common to both: transitory optic neuritis and retrolaminar demyelinating optic neuropathy with scotoma of the central visual field (which occasionally manifests as unilateral temporary blindness (85, 138, 163).

In fact, these opthomological symptoms have been thought of for years in their respective literatures to be "tell tale" indications for the differential diagnosis for each of these maladies independently (85, 138, 148, 163, 169).

The common symptoms of
headache (13, 83, 181, 189)
nervousness (13, 83, 181)
depression (58, 83, 189, 181)
memory loss (18, 147, 85, 169, 181)
tingling sensations (13, 85, 168, 138, 169)
pain in the extremities (13, 85, 169)
optic neuritis (85, 138, 148, 163, 169)
bright lights in the visual field (139, 83)
seizures (21, 83, 160)
inability to urinate or to keep from urinating (139, 146, 167)
are all shared by each of these conditions and shared yet again by complaints from aspartame poisoning (54, 58, 93, 181).

I take these strikingly similar symptom patterns as evidence that these disorders act on identical components of the central nervous system and in the same way.

The "Miracle" that MS shares with Methanol poisoning

In the early stages of MS, or when a non-lethal dose of methanol has been administered, complete recovery is a possibility.

The only two afflictions for which such dramatic "remissions" are reported from identical neuromuscular and opthomological damage, even "blindness" is relapsing-remitting multiple sclerosis (85) and methyl alcohol poisoning (138, 163).

The pathology of the two maladies is in may ways identical, particularly when it comes to destruction of the myelin sheath with no harm to the axon itself (18, 148, 176).

Sex Ratios for MS and Aspartame Reactions

Women bear the brunt of multiple sclerosis (91a-c) and lupus (SLE)(73) with fully three-fold representations in infliction numbers over men for both diseases.

This is exactly the proportion represented by adverse reactors to Aspartame reported by the US Center for Disease Control in their study of 1984 (58).

The Center found three women to every man whose Aspartame consumption complaints were serious enough to warrant investigation (93).

Although the female/male ratio for those stricken with MS has always been high, recent estimates place it at over 3 to 1 (91, 91a, 91c).

What might account for the difference across sexes in incidence?

A study published in the New England Journal of Medicine (94) reports biopsies of the gastric lining of men and women.

A result was that the concentration of ADH in the gastric lining of men was much higher than for woman.

Men have the advantage of removing methanol from the bloodstream four times faster on an equal-body-size basis than women.

Thus, for men, methanol is more likely to be removed from the blood before it reaches the brain.

The brain is spared but the methanol removed would still be metabolized to formaldehyde in the gut where it would reap its havoc on a more forgiving organ.

This may help explain why men have more gastrointestinal complaints from both methanol and Aspartame consumption (93, 99).

On the other hand, women's complaints from both more frequently involve serious neurological complications."


Methanol (11% of aspartame), made by body into formaldehyde in many vulnerable tissues, causes modern diseases of civilization, summary of a century of research, Woodrow C Monte PhD, Medical Hypotheses journal: Rich Murray 2009.11.15
Sunday, November 15, 2009
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Formaldehyde from 0.2 mg daily methanol from aspartame in Singulair (montelukast) chewable asthma medicine causes severe allergic dermatitis in boy, SE Jacob et al, Pediatric Dermatology 2009 Nov: Rich Murray 2010.09.27
Monday, September 27, 2010
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Rich Murray, MA
Boston University Graduate School 1967 psychology
BS MIT 1964, history and physics
1943 Otowi Road
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